The international airports of the country are served by the major airlines of the world, with regional flights from Buenos Aires, Porto Alegre, San Pablo, Río de Janeiro, Asunción, Panama, Santiago de Chile and Lima. Additionally, international flights arrive in Uruguay from the United States and Europe. The main airports are the International Airport of Carrasco (18 kilometers from the center of Montevideo), the International Airport Laguna del Sauce in Punta del Este (Maldonado) and the airport in Colonia de Sacramento, International Airport Laguna de los Patos. The new, International Airport of Carrasco was inaugurated in 2009 and is considered one of the most modern and attractive airports in the world. From there you have easy access to the center of Montevideo as well as the east coast with direct buses traveling in both directions. It is also easy to hire a private transfer, take a taxi or rent a car from some of the local car rental agencies in the airport.

There are numerous boats and ferries linking Buenos Aires with Colonia, Carmelo and Montevideo that also allow the transport of automobiles. Many marinas also allow access to private boats. The two companies, Buquebus and Colonia Express arrive at the port of Colonia. Both companies offer a package deal that includes a bus transfer from the Colonia port to Montevideo or Punta del Este. Buquebus and Colonia Express also offer boat and ferry services directly to Montevideo. The company Cacciola operates between Tigre and Carmelo with packages that include the ground transfers to Buenos Aires and Montevideo.